What is CAD analysis?

Besides surfactant characterization, CAD analysis finds application for excipient quantification in general. We provide all our analytical services with the highest quality standards. Each project is carried out by experienced scientists and every report or data presentation is comprehensively checked by a scientific reviewer.

How do CADS convert an analyte to a detectable signal?

All CADs utilize evaporative technology and the conversion of an analyte to a detectable signal involves the same successive steps: 1. Nebulization: Charged Aerosol Detection begins by nebulizing the column eluent into droplets and subsequently drying the droplets into particles. The particle size increases with the amount of analyte. 2.

How does CAD work?

In the case of CAD, the analyte particles are subsequently positively charged by a secondary nitrogen stream. The final detection of these dried particles, all nonvolatile, takes place by means of light scattering (photomultiplier) or level of electrical charge (electrometer) for CAD, respectively.

How does HPLC CAD work?

Detection: charged aerosol particles transfer to a collector, where an extremely sensitive electrometer measures the aggregate charge. This process generates a signal directly proportional to the mass of the analyte present. Discover how the CAD can benefit your HPLC analysis. Learn best lab practices for setting up your HPLC-CAD system.